Pre-visit lab checklist
Choose where you are in GLP-1 therapy and tick the conditions that apply. The tool builds a printable checklist of labs to ask about, questions for the visit, tests the labels say are not routine, and the symptoms that would change the plan. Every line cites the FDA label or guideline it comes from. No diagnoses, no scores, no doses.
Your situation
You are being evaluated or have a first visit booked.
Checklist for your visit (10 items)
Prepared 2026-09-04 for before a first prescription. Take it to the visit and ask; your prescriber decides what to order.
Labs to ask about
Hemoglobin A1c, and a fasting glucose if one has not been done recently
Establishes where glucose sits before therapy. The diagnostic cut points are under 5.7%, 5.7% to 6.4% and 6.5% or higher.
Source: MedlinePlus: A1C test (https://medlineplus.gov/ency/article/003640.htm) | Read more
Lipid panel (total, LDL, HDL, triglycerides)
A baseline to compare against later. The ADA Standards include a lipid profile in the initial evaluation for people with diabetes.
Source: American Diabetes Association, Standards of Care in Diabetes 2026 (https://professional.diabetes.org/standards-of-care) | Read more
Comprehensive metabolic panel: creatinine with eGFR, electrolytes, ALT and AST
Kidney and liver function before starting give the numbers to compare against if you later become dehydrated or unwell.
Source: American Diabetes Association, Standards of Care in Diabetes 2026 (https://professional.diabetes.org/standards-of-care) | Read more
Complete blood count, if your prescriber orders a baseline panel
Not required by any GLP-1 label. A baseline hemoglobin matters later because anemia can distort A1c.
Source: MedlinePlus: CBC blood test (https://medlineplus.gov/ency/article/003642.htm) | Read more
Questions for the visit
Tell your prescriber about any personal or family history of medullary thyroid carcinoma or MEN 2
That history is a contraindication in every semaglutide and tirzepatide label. It is a question, not a lab test.
Source: Zepbound (tirzepatide) prescribing information, DailyMed set id 487cd7e7-434c-4925-99fa-aa80b1cc776b (https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b) | Read more
Tests that are not routine (so you are not surprised when they are not ordered)
Calcitonin and thyroid ultrasound are not routine tests on GLP-1 therapy
The labels state that routine monitoring of serum calcitonin or thyroid ultrasound is of uncertain value for early detection of medullary thyroid carcinoma. They do say a thyroid nodule found on exam or imaging should be evaluated. Mention any neck lump, trouble swallowing or persistent hoarseness.
Source: Wegovy (semaglutide) prescribing information, DailyMed set id ee06186f-2aa3-4990-a760-757579d8f77b (https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ee06186f-2aa3-4990-a760-757579d8f77b) | Read more
Routine lipase or amylase is not asked for by the labels
The labels report mean rises in amylase and lipase on treatment and state that the clinical significance of those rises is unknown in the absence of other signs and symptoms of pancreatitis. They ask prescribers to watch for symptoms instead.
Source: Zepbound (tirzepatide) prescribing information, DailyMed set id 487cd7e7-434c-4925-99fa-aa80b1cc776b (https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b) | Read more
Vitamin D testing is not routine for healthy adults
The 2024 Endocrine Society guideline suggests against routine 25-hydroxyvitamin D testing in healthy adults. Ask only if you have a reason, such as a bone condition or a previous low result.
Source: Endocrine Society, Vitamin D for the Prevention of Disease guideline, 2024. PubMed 38828931 (https://pubmed.ncbi.nlm.nih.gov/38828931/) | Read more
Symptoms that change the plan (labs or imaging are done when these appear)
Persistent or severe abdominal pain, sometimes radiating to the back, with or without vomiting
The label language for suspected pancreatitis. Stop and seek care; lipase is drawn then, not on a schedule.
Source: Wegovy (semaglutide) prescribing information, DailyMed set id ee06186f-2aa3-4990-a760-757579d8f77b (https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ee06186f-2aa3-4990-a760-757579d8f77b) | Read more
Pain in the upper right abdomen, fever, yellowing of the skin or eyes, or pale stools
The labels say that if cholelithiasis or cholecystitis is suspected, gallbladder studies and clinical follow-up are indicated. Imaging is done when symptoms appear, not routinely.
Source: Zepbound (tirzepatide) prescribing information, DailyMed set id 487cd7e7-434c-4925-99fa-aa80b1cc776b (https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=487cd7e7-434c-4925-99fa-aa80b1cc776b) | Read more
This is a list of things to ask about, built from the FDA labels for the approved products and from published guidelines. It is not a diagnosis, an order set or medical advice. Reference ranges vary by laboratory and interpretation belongs to your clinician. Compounded semaglutide and tirzepatide are not FDA approved and are not interchangeable with the brand products the labels describe.
Formulashown in full, nothing hidden
checklist = stage items (baseline labs before therapy; renal function and symptom watch while starting; repeat intervals later)
+ one block per ticked condition (diabetes -> A1c on the ADA schedule; kidney or GI symptoms -> creatinine, eGFR, electrolytes; ...)
+ always: calcitonin and lipase listed as NOT routine, with the label sentence that says so
+ always: the pancreatitis and gallbladder symptom lines from the labels
duplicates collapse to one item; no weights, no score, no verdictEvery line on the output traces to one source you can open. Ticking a box never produces a diagnosis; it adds the questions that source attaches to that situation.
Assumptions, checked September 4, 2026
- Label statements come from the Wegovy (revised June 2026), Ozempic (June 2026), Zepbound and Mounjaro (September 2026) prescribing information on DailyMed, read on the date above.
- ADA intervals (A1c twice a year at goal or quarterly otherwise, annual eGFR and urine albumin in type 2 diabetes, periodic B12 on metformin, lipids after a statin change and then yearly) are from the Standards of Care in Diabetes 2026.
- KDIGO 2024 defines the eGFR and albuminuria categories used in the kidney items. The Endocrine Society 2024 guideline is the source for vitamin D testing not being routine.
- The checklist assumes an adult in the United States prescribed semaglutide or tirzepatide. It does not cover liraglutide, dulaglutide, exenatide or pediatric use.
This calculator is an arithmetic aid for medication a licensed prescriber has already prescribed. It does not recommend a dose. Confirm any result with your prescriber or pharmacist before use.
Sources
- Wegovy (semaglutide) prescribing information, DailyMed set id ee06186f-2aa3-4990-a760-757579d8f77b (boxed warning, sections 5.1 to 5.5, 8.3)
- Zepbound (tirzepatide) prescribing information, DailyMed set id 487cd7e7-434c-4925-99fa-aa80b1cc776b (sections 5.1 to 5.8, 6.1, 7.2, 8.3)
- Ozempic (semaglutide) prescribing information, DailyMed set id adec4fd2-6858-4c99-91d4-531f5f2a2d79
- American Diabetes Association, Standards of Care in Diabetes 2026
- KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of CKD. PubMed 38490803
- Endocrine Society, Vitamin D for the Prevention of Disease, 2024. PubMed 38828931
- NIH Office of Dietary Supplements, Vitamin B12 fact sheet for health professionals
- FDA: FDA's concerns with unapproved GLP-1 drugs used for weight loss
Read before you use it
Guides for this calculator
From the FormBlends network
Sister sites
- FormBlends Guides · Long-form how-tos for life on a GLP-1, sourced to the label.
- Tirzepatide Hub · Titration dates, vial units, missed doses and self-pay costs for tirzepatide, with the label and trial numbers behind each one.
- Semaglutide Hub · Ozempic, Wegovy, Rybelsus and compounded semaglutide, by the label and by the numbers.
- FormBlends Calculators · Dosing arithmetic, shown step by step.
Educational, not medical advice. Read the medical disclaimer.